Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 8/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8306913 | 0.99 | BRS3 (0.51) | BRS3HRH3EP300AOC3CYP11B1 | |
| SCHEMBL7919393 | 0.85 | BRS3 (0.62) | BRS3HRH3EP300AOC3CYP11B1 | |
| Hydrochloric Acid SCHEMBL8521500 | 0.84 | BRS3 (0.61) | BRS3HRH3EP300AOC3CYP11B1 | |
| SCHEMBL8193745 | 0.82 | BRS3 (0.50) | BRS3HRH3EP300AOC3CYP11B1 | |
| Hydrochloric Acid SCHEMBL8308875 | 0.81 | BRS3 (0.49) | BRS3HRH3EP300AOC3CYP11B1 | |
| SCHEMBL7924356 | 0.81 | BRS3 (0.72) | BRS3HRH3 | |
| Hydrochloric Acid SCHEMBL8309282 | 0.80 | BRS3 (0.71) | BRS3HRH3 | |
| SCHEMBL8308371 | 0.79 | BRS3 (0.56) | BRS3HRH3EP300AOC3CYP11B1 | |
| Hydrochloric Acid SCHEMBL8304730 | 0.78 | BRS3 (0.55) | BRS3HRH3EP300AOC3CYP11B1 | |
| Trifluoroacetic Acid SCHEMBL8309330 | 0.77 | BRS3 (0.61) | BRS3EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891361-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036901-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891361-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036901-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |