Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311182 | 0.88 | RXFP1 (0.61) | RXFP1LMNATHRBKMT2AHTT | |
| SCHEMBL8311184 | 0.87 | RXFP1 (0.60) | RXFP1LMNATHRBKMT2AHTT | |
| SCHEMBL8311661 | 0.84 | RXFP1 (0.58) | ATMRXFP1LMNATHRBKMT2A | |
| SCHEMBL8305683 | 0.81 | RXFP1 (0.60) | RXFP1LMNATHRBKMT2ATDP1 | |
| SCHEMBL8311517 | 0.79 | RXFP1 (0.58) | RXFP1LMNATHRBKMT2ATDP1 | |
| SCHEMBL8305679 | 0.79 | RXFP1 (0.71) | RXFP1LMNATHRBKMT2APOLB | |
| SCHEMBL8305681 | 0.78 | RXFP1 (0.66) | RXFP1LMNATHRBKMT2ACYP2C9 | |
| SCHEMBL30948385 | 0.78 | RXFP1 (0.60) | ATMRXFP1LMNAKMT2ACYP2C9 | |
| SCHEMBL13253403 | 0.78 | KDM4E (0.71) | ATMCYP2C9TDP1POLBRAB9A | |
| SCHEMBL8311188 | 0.77 | KMT2A (0.74) | ATMRXFP1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |