Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303993 | 0.93 | TP53 (0.60) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8311545 | 0.90 | MAPT (0.73) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8304143 | 0.86 | MEN1 (0.69) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8312500 | 0.85 | TP53 (0.78) | TP53MAPTPOLBBACE1LMNA | |
| SCHEMBL8307061 | 0.85 | MAPT (0.73) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8304419 | 0.85 | MAPT (0.83) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8312249 | 0.85 | MEN1 (0.56) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8312689 | 0.85 | MEN1 (0.56) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8307119 | 0.85 | MAPT (0.59) | TP53MAPTPOLBMEN1KMT2A | |
| SCHEMBL8303990 | 0.85 | KDM4E (0.63) | TP53MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |