Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308525 | 1.00 | PPARG (0.59) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL8304312 | 1.00 | PPARG (0.59) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL8305247 | 0.90 | PPARG (0.63) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL8406934 | 0.90 | PPARG (0.63) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL8305440 | 0.90 | PPARG (0.63) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL8305245 | 0.90 | PPARG (0.63) | PPARGADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9413146 | 0.86 | PPARG (0.47) | PPARGFFAR1CYP2C9 | |
| SCHEMBL9413145 | 0.86 | PPARG (0.47) | PPARGFFAR1CYP2C9 | |
| SCHEMBL6930080 | 0.85 | PPARG (0.76) | PPARGFFAR1CYP2C9 | |
| SCHEMBL6929663 | 0.85 | PPARG (0.76) | PPARGFFAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590793-B1 | Oxazolidine derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO CO (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5436257-A | Low toxicity | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0590793-A1 | Oxazolidine derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-04-06 | — | — | EP | disclosed |