Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621753 | 0.74 | HDAC6 (0.47) | PDE3BPDE3AALDH1A1NPSR1TSHR | |
| SCHEMBL18643654 | 0.70 | PDE3B (0.50) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL14176442 | 0.68 | PDE3B (0.45) | PDE3BPDE3AALDH1A1LMNAESR2 | |
| SCHEMBL5121211 | 0.67 | ESR2 (0.67) | ALDH1A1KDM4ELMNAESR2ESR1 | |
| SCHEMBL3279554 | 0.67 | CTNNB1 (0.52) | ALDH1A1KDM4ELMNAGAAHSD17B10 | |
| SCHEMBL5117114 | 0.66 | HRH3 (0.50) | PDE3BPDE3AALDH1A1LMNAGAA | |
| SCHEMBL3286540 | 0.66 | POLB (0.42) | ALDH1A1GAAF12MEN1MAPT | |
| SCHEMBL9172861 | 0.66 | CTNNB1 (0.51) | ALDH1A1KDM4ELMNAGAAHSD17B10 | |
| SCHEMBL5120987 | 0.65 | PDE3B (0.45) | PDE3BPDE3AALDH1A1LMNAHSD17B10 | |
| SCHEMBL5121850 | 0.64 | PDE3B (0.47) | PDE3BPDE3AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786996-A4 | CYSTEINE PROTEASE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0786996-A1 | CYSTEINE PROTEASE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-06 | — | — | EP | disclosed |