Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232502 | 0.86 | PDE1A (0.30) | PDE1APDE1BPDE1C | |
| SCHEMBL5335326 | 0.85 | EGLN2 (0.31) | — | |
| SCHEMBL5266946 | 0.84 | PDE1A (0.31) | PDE1APDE1BPDE1C | |
| SCHEMBL6090496 | 0.84 | — | — | |
| SCHEMBL8302482 | 0.83 | KDR (0.34) | — | |
| SCHEMBL5262375 | 0.78 | ADORA2A (0.33) | KCNH2 | |
| SCHEMBL8302533 | 0.78 | — | — | |
| SCHEMBL5780465 | 0.77 | ADORA2A (0.32) | KCNH2 | |
| SCHEMBL5780711 | 0.77 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL6101337 | 0.75 | KCNH2 (0.32) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004107863-A1 | SUSTITUTED IMIDAZOLOPYRAZINE AND TRIAZOLOPYRAZINE DERIVATIVES: GABAA RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2004-12-16 | — | — | WO | disclosed |