Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424625 | 0.89 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3424622 | 0.89 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL8302314 | 0.79 | DPP4 (0.79) | DPP4CYP3A4 | |
| SCHEMBL3425436 | 0.78 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL8306122 | 0.77 | DPP4 (0.80) | DPP4CYP3A4 | |
| SCHEMBL3427608 | 0.76 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3427609 | 0.76 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL555439 | 0.75 | DPP4 (0.79) | DPP4 | |
| SCHEMBL14258037 | 0.75 | DPP4 (0.79) | DPP4 | |
| SCHEMBL8234627 | 0.74 | DPP4 (0.77) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608317-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2012-09-26 | — | — | EP | disclosed |
| WO-2004087053-A9 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX INC (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | disclosed |