Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304974 | 1.00 | PPARG (0.54) | PPARGHTTESR1MAPTFFAR1 | |
| SCHEMBL8310074 | 0.93 | PPARG (0.54) | PPARGHTTMAPTFFAR1RXRA | |
| SCHEMBL8310076 | 0.93 | PPARG (0.54) | PPARGHTTMAPTFFAR1RXRA | |
| SCHEMBL8305087 | 0.91 | PPARG (0.51) | PPARGHTTESR1MAPTFFAR1 | |
| SCHEMBL8305089 | 0.91 | PPARG (0.51) | PPARGHTTESR1MAPTFFAR1 | |
| SCHEMBL8305869 | 0.91 | PPARG (0.52) | PPARGHTTFFAR1RXRARARG | |
| SCHEMBL8305873 | 0.91 | PPARG (0.52) | PPARGHTTFFAR1RXRARARG | |
| SCHEMBL8305170 | 0.89 | PPARG (0.69) | PPARGHTTMAPTFFAR1RXRA | |
| SCHEMBL8305173 | 0.89 | PPARG (0.69) | PPARGHTTMAPTFFAR1RXRA | |
| SCHEMBL8307060 | 0.86 | PPARG (0.55) | PPARGHTTMAPTFFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |