SCHEMBL8305093

SCHEMBL8305093

Cn1nc(C(F)(F)F)c(Cl)c1-n1nn[nH]c1=O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
RECQL P46063 1/20 0.32
MAPK8 P45983 2/20 0.32
NOTUM Q6P988 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
DYRK3 O43781 1/20 0.30
PIM1 P11309 1/20 0.30
MAPK9 P45984 1/20 0.30
MAPK10 P53779 1/20 0.30
DYRK1A Q13627 1/20 0.30
NTRK3 Q16288 1/20 0.30
PIM3 Q86V86 1/20 0.30
SRPK1 Q96SB4 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8304232 0.79 KDM4E (0.37) KDM4ELMNAKMT2A
SCHEMBL8521551 0.75
SCHEMBL8309135 0.75 CYP2C9 (0.37)
SCHEMBL8303635 0.70 PRMT5 (0.37) LMNA
SCHEMBL8308478 0.67 POLB (0.32) LMNA
SCHEMBL8302486 0.67 BPTF (0.33)
SCHEMBL8308505 0.67 PRMT5 (0.38) KDM4EKMT2A
SCHEMBL8551900 0.65 KDM4E (0.44) KDM4ERECQLMAPK8LMNAKMT2A
SCHEMBL17207364 0.65 KMT2A (0.42) KDM4ERECQLMAPK8NOTUMLMNA
SCHEMBL8306156 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed