Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397723 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL2304824 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL800116 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL30905336 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL3732469 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL29400850 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3 | |
| SCHEMBL3224249 | 0.83 | MDM4 (0.44) | MDM4TP53MDM2CASP3TNF | |
| SCHEMBL3264342 | 0.83 | MDM4 (0.44) | MDM4TP53MDM2CASP3TNF | |
| SCHEMBL3729019 | 0.82 | MDM4 (0.53) | MDM4TP53MDM2CASP3PTPN1 | |
| SCHEMBL3729015 | 0.82 | MDM4 (0.53) | MDM4TP53MDM2CASP3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004094461-A2 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |