SCHEMBL830594

SCHEMBL830594

[CH]1OC=CC=CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181346 0.74
SCHEMBL2479932 0.71
SCHEMBL30978372 0.70
Ammonia Solution, Strong SCHEMBL30978376 0.70
Hydrochloric Acid SCHEMBL27868973 0.70
Hydrogen Sulfide SCHEMBL28797397 0.70
SCHEMBL27938586 0.70
SCHEMBL15522455 0.65
SCHEMBL4077 0.64
SCHEMBL626538 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022199-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2016-05-25 EP claimed
WO-2015008872-A1 CYANOTRIAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2015-01-22 WO claimed
CN-109195965-B Inhibitors of WDR5 protein-protein binding 普罗佩纶治疗公司 2022-07-26 CN disclosed
US-20150335624-A1 COMPOSITIONS AND METHODS FOR USING HUPERZINE AND ANALOGS THEREOF INSERO HEALTH INC (US) 2015-11-26 US disclosed
US-20150191430-A1 CONJUGATES OF HUPERZINE AND ANALOGS THEREOF BISCAYNE NEUROTHERAPEUTICS, INC. 2015-07-09 US disclosed
US-20130296226-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC DISORDERS HALIMED PHARMACEUTICALS INC (US) 2013-11-07 US disclosed
WO-2013166468-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INSERO HEALTH INC. (US) 2013-11-07 WO disclosed
US-8476221-B2 Methods and compositions for the treatment of metabolic disorders HALIMED PHARMACEUTICALS, INC. (US) 2013-07-02 US disclosed
US-20120238490-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC DISORDERS HALIMED PHARMACEUTICALS, INC. 2012-09-20 US disclosed
US-20120142601-A1 Modified Peptides and Uses Thereof MUSC FOUNDATION FOR RESEARCH DEVELOPMENT 2012-06-07 US disclosed
EP-1773310-B9 ALPHA, BETA-UNSATURATED SULFONES, SULFOXIDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES AND ACYLSULFINAMIDES AND THERAPEUTIC USES THEREOF UNIV TEMPLE (US) 2012-04-25 EP disclosed
EP-0882701-B1 SUBSTITUTED AMIDE DERIVATIVES BANYU PHARMA CO LTD (JP) 2002-07-24 EP disclosed
EP-1165515-A1 PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP disclosed
WO-2000058288-A1 PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES BASF AKTIENGESELLSCHAFT (DE) 2000-10-05 WO disclosed
US-6048894-A FARNESYL-PROTEIN TRANSFERASE INHIBITORS, ANTITUMOR OR ANTICANCER AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-04-11 US disclosed
US-6011174-A INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-01-04 US disclosed
EP-0882703-A1 CYCLIC AMIC ACID DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0882701-A1 SUBSTITUTED AMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed
US-5597776-A ANTAGONIST FOR HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-01-28 US disclosed
EP-0537463-A2 Substituted pyrido(2,3-d)pyrimidines as antidotes BASF Aktiengesellschaft (DE) 1993-04-21 EP disclosed