Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6332620 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6324371 | 0.88 | HPGD (0.44) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| SCHEMBL6321686 | 0.87 | CDK1 (0.44) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6325009 | 0.83 | HPGD (0.43) | SMN1; SMN2HPGDMAPTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL6332596 | 0.83 | HPGD (0.43) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| SCHEMBL6329307 | 0.82 | HPGD (0.40) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6324987 | 0.81 | F10 (0.39) | SMN1; SMN2HPGDLMNAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6322311 | 0.81 | EGFR (0.40) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6321548 | 0.79 | PDE5A (0.37) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| SCHEMBL6324788 | 0.78 | HPGD (0.41) | SMN1; SMN2HPGDNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |