Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.99 |
| ▸ | CTSD | P07339 | 19/20 | 0.99 |
| ▸ | BACE2 | Q9Y5Z0 | 19/20 | 0.99 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930522 | 1.00 | BACE1 (0.99) | BACE1CTSDBACE2 | |
| SCHEMBL5930035 | 0.99 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL5929977 | 0.99 | BACE1 (0.96) | BACE1CTSDBACE2 | |
| SCHEMBL5930405 | 0.97 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| Formic Acid SCHEMBL5930118 | 0.97 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL5930276 | 0.94 | BACE1 (0.91) | BACE1CTSDBACE2 | |
| Formic Acid SCHEMBL5930264 | 0.94 | BACE1 (0.94) | BACE1CTSDBACE2 | |
| SCHEMBL5930228 | 0.94 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL5930234 | 0.93 | BACE1 (0.88) | BACE1CTSDBACE2 | |
| SCHEMBL5930004 | 0.92 | BACE1 (1.00) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004094430-A1 | TRICYCLIC INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER’S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-11-04 | — | — | WO | disclosed |