Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.50 |
| ▸ | CPT1A | P50416 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182343 | 0.93 | CPT2 (0.51) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL7290318 | 0.93 | CPT2 (0.51) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL8994561 | 0.89 | CPT2 (0.48) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL7282427 | 0.88 | NPC1 (0.56) | CPT2CPT1AACENPC1RAB9A | |
| Water SCHEMBL7282829 | 0.87 | NPC1 (0.55) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL7291237 | 0.86 | NPC1 (0.53) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL7294666 | 0.86 | NPC1 (0.53) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL9485197 | 0.85 | ACE (0.57) | CPT2CPT1AACENPC1RAB9A | |
| SCHEMBL8994613 | 0.83 | CCR1 (0.50) | RAB9A | |
| SCHEMBL7283694 | 0.82 | NPC1 (0.53) | CPT2CPT1AACENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-B1 | N-acylpyrrolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO (JP) | 1999-08-25 | — | — | EP | disclosed |
| US-5545657-A | 1-ALKYLOYLPYRROLIDIN-2-YLOXOALKANOIC ACIDS AND DERIVATIVES; ANTIAMNESIA AGENTS; INHIBITORS OF PROLYL ENDOPEPTIDASE; SUPPRESSION OF NEUROTRANSMITTER METABOLISM | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| US-5411974-A | Thiazoline derivatives, treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| US-5401760-A | Thiazoline derivative for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5212191-A | Thiazoline derivatives for treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0537802-A2 | N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5053414-A | Thiazolidine derivatives, enzyme inhibitors; amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |