⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11471359 | 0.98 | GSK3B (0.57) | — | |
| SCHEMBL68448 | 0.81 | PTPN1 (0.54) | — | |
| SCHEMBL9259401 | 0.80 | — | — | |
| SCHEMBL28655905 | 0.78 | PTPN1 (0.52) | — | |
| SCHEMBL18105662 | 0.78 | — | — | |
| SCHEMBL827117 | 0.78 | — | — | |
| SCHEMBL6790251 | 0.75 | GSK3B (1.00) | — | |
| SCHEMBL827254 | 0.73 | GSK3B (0.52) | — | |
| SCHEMBL18047964 | 0.73 | GSK3B (0.52) | — | |
| SCHEMBL351965 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486882-B | Matrine alkaloid derivative and application thereof in preparation of multi-target multi-organ tissue cell injury inhibitor | 吉林农业大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-117486882-A | Matrine alkaloid derivative and application thereof in preparation of multi-target multi-organ tissue cell injury inhibitor | 吉林农业大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-116041415-B | Split-ring lupin alkane derivative, and preparation method and application thereof | 吉林农业大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-116041415-A | Split-ring lupin alkane derivative, and preparation method and application thereof | 吉林农业大学 | 2023-05-02 | — | — | CN | disclosed |
| US-11269251-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-03-08 | — | — | US | disclosed |
| EP-3267996-B1 | PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3268003-B1 | THIENOPYRAZINE INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME (US) | 2020-07-29 | — | — | EP | disclosed |
| EP-3268004-B1 | PYRROLOPYRIDAZINE INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME (US) | 2019-12-18 | — | — | EP | disclosed |
| US-10329295-B2 | Pyrrolotriazine inhibitors of IRAK4 activity | MERCK SHARP & DOHME CORP. (US) | 2019-06-25 | — | — | US | disclosed |
| US-10329294-B2 | Pyrazolopyrimidine inhibitors of IRAK4 activity | MERCK SHARP & DOHME CORP. (US) | 2019-06-25 | — | — | US | disclosed |
| EP-0695748-B1 | Tetrazolinone herbicides | BAYER AGROCHEM KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5589439-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0695748-A1 | Tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-4230873-A | Thiophene derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4224445-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4177193-A | ALKOXYCARBONYL, ALKYLAMINOSULFONYL-SUBSTITUTED THIOPHENE INTERMEDIATES FOR THE 4-HYDROXY-N-SUBSTITUTED-2H-THIENO(2,3-E)-1,2-THIAZINE-3-CARBOXAMIDE-1,1 -DIOXIDES; ANTIINFLAMMATORY, ANALGESIC | HOFFMAN-LA ROCHE INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4134898-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4076709-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4032647-A | HYPOLIPIDEMIC AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4028373-A | ARTIFICIAL SWEETNERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |