Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.61 |
| ▸ | TACR2 | P21452 | 2/20 | 0.61 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366587 | 0.90 | TACR2 (0.60) | TACR1TACR2CCR5TACR3 | |
| SCHEMBL9027911 | 0.90 | TACR2 (0.60) | TACR1TACR2CCR5TACR3 | |
| SCHEMBL9028189 | 0.90 | TACR2 (0.60) | TACR1TACR2CCR5TACR3 | |
| SCHEMBL7956505 | 0.90 | TACR2 (0.65) | TACR1TACR2CCR5 | |
| SCHEMBL8953928 | 0.88 | TACR1 (0.59) | TACR1TACR2CCR5TACR3 | |
| SCHEMBL5134674 | 0.88 | TACR2 (0.62) | TACR1TACR2CCR5 | |
| SCHEMBL8953983 | 0.87 | TACR2 (0.64) | TACR1TACR2 | |
| SCHEMBL8953856 | 0.87 | TACR2 (0.61) | TACR1TACR2CCR5TACR3 | |
| SCHEMBL8882429 | 0.85 | TACR2 (0.65) | TACR1TACR2 | |
| SCHEMBL8883479 | 0.85 | TACR2 (0.65) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |