Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 2/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363714 | 1.00 | CD38 (0.56) | CD38IRAK4USP2LMNACYP1A2 | |
| SCHEMBL6363717 | 1.00 | CD38 (0.56) | CD38IRAK4USP2LMNACYP1A2 | |
| SCHEMBL6363833 | 0.86 | CD38 (0.54) | CD38IRAK4 | |
| SCHEMBL6368111 | 0.86 | CD38 (0.54) | CD38IRAK4 | |
| SCHEMBL6367334 | 0.86 | CD38 (0.54) | CD38IRAK4 | |
| SCHEMBL6363835 | 0.84 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL6364052 | 0.82 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL6368146 | 0.77 | GRM1 (0.55) | IRAK4USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL17656889 | 0.76 | IRAK4 (0.78) | CD38IRAK4USP2LMNACYP1A2 | |
| SCHEMBL23806243 | 0.74 | IRAK4 (0.81) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016925-A1 | AZAQUINAZOLINE DERIVATIVES | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |