Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 15/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 15/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 15/20 | 0.67 |
| ▸ | F2 | P00734 | 6/20 | 0.63 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8312274 | 0.89 | F10 (0.61) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8311347 | 0.88 | F10 (0.64) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8308987 | 0.87 | F10 (0.63) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8308177 | 0.86 | F10 (0.64) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8308626 | 0.84 | F10 (0.50) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8307769 | 0.84 | F10 (0.67) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8311996 | 0.83 | F10 (0.65) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8312004 | 0.82 | F10 (0.68) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8311383 | 0.82 | F10 (0.68) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8312401 | 0.82 | F10 (0.65) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937723-A1 | Novel sulfonamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |