Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MPC2 | O95563 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440663 | 0.96 | HRH3 (0.55) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8304663 | 0.89 | HRH3 (0.56) | FFAR1PPARGHRH3PPARAMEN1 | |
| SCHEMBL9440668 | 0.87 | FFAR1 (0.46) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8975030 | 0.85 | FFAR1 (0.52) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8303956 | 0.83 | PPARG (0.48) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8303702 | 0.83 | PPARG (0.48) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8309318 | 0.81 | PPARG (0.46) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8309316 | 0.81 | PPARG (0.46) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8974565 | 0.80 | FFAR1 (0.49) | FFAR1PPARGHRH3PPARAMPC2 | |
| SCHEMBL8307509 | 0.79 | PPARG (0.47) | FFAR1PPARGHRH3PPARAMPC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590793-B1 | Oxazolidine derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO CO (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5436257-A | Low toxicity | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0590793-A1 | Oxazolidine derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-04-06 | — | — | EP | disclosed |