Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305215 | 1.00 | EPHX1 (0.45) | EPHX1IDO1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7294198 | 0.77 | EPHX1 (0.55) | EPHX1IDO1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28574749 | 0.70 | EPHX1 (0.38) | EPHX1SLC6A3SLC6A2SLC6A4HSD17B2 | |
| SCHEMBL21175346 | 0.70 | EPHX1 (0.44) | EPHX1IDO1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL14895451 | 0.70 | CYP1A2 (0.37) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28573814 | 0.69 | EPHX1 (0.40) | EPHX1SLC6A3SLC6A2SLC6A4HSD17B2 | |
| Isopropylbenzene SCHEMBL28915614 | 0.69 | GRM2 (0.36) | ALDH1A1 | |
| SCHEMBL28451662 | 0.68 | — | — | |
| SCHEMBL10067167 | 0.68 | EPHX1 (0.45) | EPHX1IDO1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6526560 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835254-B1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1999-09-01 | — | — | EP | disclosed |
| US-5843975-A | Oxazolidinone derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1998-12-01 | — | — | US | disclosed |
| WO-1996038444-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1996-12-05 | — | — | WO | disclosed |