Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.76 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308613 | 1.00 | PPARG (0.76) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6904420 | 0.90 | PPARG (0.72) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6904419 | 0.90 | PPARG (0.72) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6898686 | 0.89 | PPARG (0.73) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6898681 | 0.89 | PPARG (0.73) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6902809 | 0.87 | PPARG (0.77) | PPARGFFAR1RXRACYP3A4RARG | |
| SCHEMBL6902815 | 0.87 | PPARG (0.77) | PPARGFFAR1RXRACYP3A4RARG | |
| SCHEMBL6902220 | 0.86 | PPARG (0.70) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6902217 | 0.86 | PPARG (0.70) | PPARGFFAR1PPARARXRACYP3A4 | |
| SCHEMBL6898697 | 0.86 | PPARG (1.00) | PPARGFFAR1RXRACYP3A4RARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |