Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.74 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83766 | 0.91 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL1136421 | 0.91 | GSK3B (0.79) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88515 | 0.91 | GSK3B (0.79) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88072 | 0.90 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88070 | 0.90 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88048 | 0.90 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88051 | 0.90 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88092 | 0.89 | GSK3B (0.76) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL81409 | 0.89 | GSK3B (0.76) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL83397 | 0.89 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805164-B9 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-09-07 | — | — | EP | claimed |
| EP-1805164-B1 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-02-23 | — | — | EP | claimed |
| EP-1805164-B9 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-09-07 | — | — | EP | disclosed |
| EP-1805164-B1 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-02-23 | — | — | EP | disclosed |