Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308951 | 1.00 | PPARG (0.38) | PPARGFFAR1NPC1GAARAB9A | |
| SCHEMBL8305071 | 0.95 | PPARG (0.37) | PPARGFFAR1CTSKMAPTRARG | |
| SCHEMBL8305072 | 0.95 | PPARG (0.37) | PPARGFFAR1CTSKMAPTRARG | |
| SCHEMBL8307315 | 0.94 | PPARG (0.36) | PPARGFFAR1CTSKMAPTRARG | |
| SCHEMBL8307312 | 0.94 | PPARG (0.36) | PPARGFFAR1CTSKMAPTRARG | |
| SCHEMBL8304613 | 0.92 | FFAR1 (0.41) | PPARGFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8304616 | 0.92 | FFAR1 (0.41) | PPARGFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8310116 | 0.92 | TAAR1 (0.44) | PPARGFFAR1GAASMN1; SMN2RARG | |
| SCHEMBL8310110 | 0.92 | TAAR1 (0.44) | PPARGFFAR1GAASMN1; SMN2RARG | |
| SCHEMBL8306092 | 0.91 | PPARG (0.35) | PPARGFFAR1RAB9ACTSKRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |