SCHEMBL8309050

SCHEMBL8309050

O=C(NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1)C(Cl)Cl

nearest known ligand 0.78

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.78
MAOA P21397 3/20 0.78
LMNA P02545 1/20 0.78
PTGS1 P23219 1/20 0.78
CALML3 P27482 1/20 0.78
SDHA P31040 1/20 0.78
F10 P00742 10/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8309053 1.00 MAOB (0.78) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5133835 0.90 F10 (0.71) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5727001 0.90 F10 (0.71) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6159613 0.90 MAOB (0.73) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6159621 0.90 MAOB (0.73) MAOBMAOALMNAPTGS1CALML3
SCHEMBL7257714 0.89 MAOB (0.78) MAOBMAOALMNAPTGS1CALML3
SCHEMBL7257717 0.89 MAOB (0.78) MAOBMAOALMNAPTGS1CALML3
SCHEMBL7262411 0.89 MAOB (0.78) MAOBMAOALMNAPTGS1CALML3
SCHEMBL3575336 0.88 MAOB (0.64) MAOBMAOALMNAPTGS1CALML3
SCHEMBL3575333 0.88 MAOB (0.64) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717738-B1 SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS UPJOHN CO (US) 1999-10-20 EP claimed