SCHEMBL8309312

SCHEMBL8309312

CC(c1ccc(F)cc1)C1CCNCC1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.58
SLC6A4 P31645 4/20 0.58
SLC6A3 Q01959 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8554853 0.98 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3
SCHEMBL28260142 0.89 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3
SCHEMBL28260140 0.89 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3
SCHEMBL19200332 0.86 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3
SCHEMBL7319671 0.85 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3
SCHEMBL20883793 0.85 SLC6A2 (0.67) SLC6A2SLC6A4SLC6A3
SCHEMBL22542178 0.83 SLC6A2 (0.60) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL9768345 0.83 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3
SCHEMBL16269909 0.82 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3
SCHEMBL12473621 0.82 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929550-A1 $i(N)-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS SYNTHELABO (FR) 1999-07-21 EP disclosed
WO-1998014444-A1 N-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS SYNTHELABO (FR) 1998-04-09 WO disclosed