Prochloraz

Prochloraz

SCHEMBL8309313

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1.O=C(c1ncc[nH]1)c1ncc[nH]1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.82
ADRB2 P07550 5/20 0.36
ADRB1 P08588 5/20 0.36
ADRB3 P13945 5/20 0.36
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 2/20 0.31
THRB P10828 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL22242 0.91 AHR (1.00) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL34675 0.91 AHR (1.00) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL9371936 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL5454581 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL11381653 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL11379280 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL12611119 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL11375792 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL11376171 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A
Prochloraz SCHEMBL10346525 0.90 AHR (0.98) AHRADRB2ADRB1ADRB3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669322-B1 Substituted sulfonamides, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-09-15 EP disclosed