Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239152 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL29808940 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL1240196 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL14490666 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL1239150 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL1134242 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL1643076 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL29809038 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL6767234 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D | |
| SCHEMBL1239149 | 1.00 | KDM1A (0.47) | KDM1AHTR2AANPEPSIGMAR1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758312-B1 | SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS | LILLY CO ELI (US) | 1999-12-22 | — | — | EP | disclosed |