Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310720 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL14521538 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL5473681 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL619526 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL3985690 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL255664 | 0.82 | CYP1A2 (0.71) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL255663 | 0.82 | CYP1A2 (0.71) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL2007222 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL255679 | 0.82 | CYP1A2 (0.71) | SMN1; SMN2POLBALDH1A1LMNACYP1A2 | |
| SCHEMBL14521516 | 0.82 | ACACB (0.49) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |