Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309114 | 0.83 | KDM4C (0.50) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL6933743 | 0.81 | KDM4C (0.43) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8305338 | 0.79 | KDM4C (0.41) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8304469 | 0.78 | KDM4C (0.42) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8307664 | 0.78 | KDM4C (0.47) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8305782 | 0.74 | KDM4C (0.55) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8309642 | 0.70 | KDM4C (0.42) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL10679113 | 0.70 | KDM4C (0.53) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL8306736 | 0.69 | KDM4C (0.48) | KDM4CMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL6879618 | 0.69 | KDM4C (0.58) | KDM4CMEN1KMT2AL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |