Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310045 | 0.98 | ACE2 (0.48) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL18024011 | 0.91 | SCN5A (0.46) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL18024053 | 0.89 | HRH3 (0.50) | ACE2CARM1PRMT6PRMT8KDM1A | |
| SCHEMBL8306450 | 0.86 | CARM1 (0.50) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL17526226 | 0.86 | ACE2 (0.58) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL17528479 | 0.84 | CARM1 (0.48) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL8307333 | 0.84 | CARM1 (0.48) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL6051858 | 0.84 | ACE2 (0.56) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL18024019 | 0.83 | ACE2 (0.52) | ACE2CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL10410535 | 0.83 | CARM1 (0.62) | ACE2CARM1PRMT6PRMT8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130968-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | YALE UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |