Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 1.00 |
| ▸ | CNR2 | P34972 | 5/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.76 |
| ▸ | MLNR | O43193 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.76 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.76 |
| ▸ | DRD1 | P21728 | 1/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.76 |
| ▸ | HRH2 | P25021 | 1/20 | 0.76 |
| ▸ | HTR2A | P28223 | 1/20 | 0.76 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.76 |
| ▸ | CCKAR | P32238 | 1/20 | 0.76 |
| ▸ | CCKBR | P32239 | 1/20 | 0.76 |
| ▸ | MC4R | P32245 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197600 | 0.95 | CNR1 (0.90) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL276640 | 0.94 | CNR1 (0.88) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL24270315 | 0.93 | CNR1 (0.88) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL277226 | 0.93 | CNR1 (0.86) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL276798 | 0.92 | CNR1 (0.85) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL276791 | 0.91 | CNR1 (0.83) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL277078 | 0.91 | CNR1 (0.83) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL277222 | 0.90 | CNR1 (0.81) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL277014 | 0.89 | CNR1 (0.80) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL277079 | 0.89 | CNR1 (0.80) | CNR1CNR2CYP2C9GPR55ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078261-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2004-09-16 | — | — | WO | disclosed |