Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426792 | 0.78 | TSHR (0.35) | TSHRACLYALDH1A1ACACBACACA | |
| SCHEMBL22955827 | 0.77 | — | — | |
| SCHEMBL12050476 | 0.76 | TSHR (0.33) | TSHRACLYALDH1A1ACACBACACA | |
| SCHEMBL8609242 | 0.74 | TSHR (0.40) | TSHRACLYALDH1A1ACACBACACA | |
| SCHEMBL23352052 | 0.73 | CYP2C19 (0.46) | TSHRCYP2D6CYP2C19 | |
| SCHEMBL163891 | 0.72 | — | — | |
| SCHEMBL16722800 | 0.71 | — | — | |
| SCHEMBL8308068 | 0.70 | CYP2C19 (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL23543049 | 0.70 | — | — | |
| SCHEMBL8312295 | 0.70 | HDAC3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |