Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.61 |
| ▸ | MAOA | P21397 | 12/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312312 | 0.93 | MAOB (0.53) | MAOBMAOAHRH3 | |
| SCHEMBL6171545 | 0.81 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL8315680 | 0.76 | MIF (0.56) | MAOBHRH3 | |
| SCHEMBL6171707 | 0.76 | MAOB (0.61) | MAOBMAOAHRH3 | |
| SCHEMBL15839887 | 0.76 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL1377016 | 0.75 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL17703887 | 0.75 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL9222772 | 0.75 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL6172712 | 0.75 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL6825904 | 0.75 | MAOB (0.67) | MAOBMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966446-A1 | BICYCLIC INHIBITORS OF PROTEIN FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998034921-A1 | BICYCLIC INHIBITORS OF PROTEIN FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1998-08-13 | — | — | WO | disclosed |