Juarezic Acid

Juarezic Acid

SCHEMBL831098

C=CC(N)=O.O=C(O)C=CC=Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.55
HDAC4 P56524 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC7 Q8WUI4 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC10 Q969S8 2/20 0.55
HDAC11 Q96DB2 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC9 Q9UKV0 2/20 0.55
HDAC5 Q9UQL6 2/20 0.55
TNKS O95271 1/20 0.55
HCAR2 Q8TDS4 1/20 0.55
TNKS2 Q9H2K2 1/20 0.55
MAOB P27338 7/20 0.50
ALDH1A1 P00352 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2D6 P10635 2/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL168964 0.91 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Acrylic Acid SCHEMBL27861204 0.90 HDAC3 (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL28990093 0.89 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL27767651 0.89 HDAC3 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL5517018 0.87 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL436113 0.87 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL11522747 0.87 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL474728 0.87 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL15119 0.87 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL144681 0.87 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240676-B Preparation method of solid polycarboxylic acid water reducing agent 武汉理工大学 2021-11-23 CN claimed
CN-116200962-A Dispersing agent, coating liquid composition, and thermosensitive recording medium 星光PMC株式会社 2023-06-02 CN disclosed
CN-110240676-B Preparation method of solid polycarboxylic acid water reducing agent 武汉理工大学 2021-11-23 CN disclosed
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2103444-B1 Thermosensitive recording material RICOH CO LTD (JP) 2012-05-30 EP disclosed
US-8143191-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-03-27 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090239746-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103444-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
US-5338406-A Using a polyelectrolyte complex HERCULES INCORPORATED (US) 1994-08-16 US disclosed
EP-0362770-B1 Dry strength additive for paper HERCULES INC (US) 1994-07-27 EP disclosed
US-5006261-A Paint detackification using water-dispersible polymeric latexes NALCO CHEMICAL COMPANY (US) 1991-04-09 US disclosed
EP-0362770-A2 Dry strength additive for paper HERCULES INCORPORATED (US) 1990-04-11 EP disclosed
US-4356109-A POLYMERIZING UREA AND FORMALDEHYDE IN PRESENCE OF ANIONIC POLYELECTROLYTE AND AN AMMONIUM SALT OF AN ACID FUJI PHOTO FILM CO., LTD. (JP) 1982-10-26 US disclosed
US-4251386-A BY POLYMERIZATION OF UREA AND FORMALDEHYDE IN AN ANIONIC POLYELECTROLYTE AND AN AMMONIUM SALT OF AN ACID FUJI PHOTO FILM CO., LTD. (JP) 1981-02-17 US disclosed
US-4221710-A PRESSURE SENSITIVE RECORDING SHEET FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US disclosed
US-4125504-A Cement additives comprising a polymer latex containing a styrene-acrylate-acrylamide interpolymer and a butadiene rubber THE DOW CHEMICAL COMPANY (US) 1978-11-14 US disclosed
US-4002588-A Hydrophilic-hydrophobic amphoteric polysalt sizing compositions and paper sized therewith AMERICAN CYANAMID COMPANY (US) 1977-01-11 US disclosed
US-3970501-A PRESSURE SENSITIVE, FORMALDEHYDE-NAPHTHALENESULFONIC ACID FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed