Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 19/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 19/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311484 | 0.94 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14422245 | 0.90 | DPP4 (0.81) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8312244 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4565776 | 0.75 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5998755 | 0.75 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4401263 | 0.74 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5489303 | 0.70 | DPP4 (0.73) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14350042 | 0.69 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL5037199 | 0.69 | DPP4 (0.72) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5487908 | 0.68 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064778-A2 | 3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO. INC. (US) | 2004-08-05 | — | — | WO | disclosed |