Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 17/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 17/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 17/20 | 0.60 |
| ▸ | PLG | P00747 | 11/20 | 0.60 |
| ▸ | F2 | P00734 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310289 | 0.97 | F10 (0.62) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8312095 | 0.96 | F10 (0.63) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8312401 | 0.92 | F10 (0.65) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8308383 | 0.91 | F10 (0.57) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8309198 | 0.91 | F10 (0.57) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8311344 | 0.91 | F10 (0.61) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8308643 | 0.90 | F10 (0.51) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8311460 | 0.90 | F10 (0.50) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8311747 | 0.90 | F10 (0.56) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8311618 | 0.89 | F10 (0.61) | F10PRSS1PRSS2PRSS3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937723-A1 | Novel sulfonamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |