Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311214 | 0.88 | S1PR1 (0.39) | S1PR1F2RL3SLC26A4MEN1KMT2A | |
| SCHEMBL8310631 | 0.83 | F2RL3 (0.35) | S1PR1F2RL3LMNANPSR1MAOB | |
| SCHEMBL8315285 | 0.81 | S1PR1 (0.35) | S1PR1F2RL3MEN1KMT2A | |
| SCHEMBL8310220 | 0.80 | KDM4E (0.43) | F2RL3LMNANPSR1MAOBSLC26A4 | |
| SCHEMBL8311729 | 0.78 | F2RL3 (0.35) | S1PR1F2RL3LMNANPSR1MAOB | |
| SCHEMBL8310770 | 0.78 | APP (0.47) | S1PR1F2RL3MAPTADRA2AADRA2B | |
| SCHEMBL8315007 | 0.77 | NPC1 (0.40) | S1PR1F2RL3LMNANPSR1MAOB | |
| SCHEMBL8311847 | 0.77 | KMT2A (0.39) | F2RL3NPSR1MEN1KMT2AMAPT | |
| SCHEMBL8317364 | 0.76 | F2RL3 (0.34) | S1PR1F2RL3LMNANPSR1MAOB | |
| SCHEMBL8310491 | 0.76 | F2RL3 (0.33) | F2RL3LMNANPSR1MAOBSLC26A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |