Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096371 | 0.83 | CYP4F2 (0.62) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL6254544 | 0.82 | CYP4F2 (0.85) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL6257314 | 0.82 | CYP4F2 (0.85) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL2895961 | 0.81 | CYP4F2 (0.61) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL7941258 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL20613555 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL20713255 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL20713329 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL31108848 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL31108907 | 0.80 | CYP4F2 (0.69) | CYP4F2CYP4A11PKMTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742200-B1 | Manufacturing method of sulphides | KONISHIROKU PHOTO IND (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0742200-A1 | Manufacturing method of sulphides | KONICA CORPORATION (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |