Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865612 | 0.92 | PDE4B (0.63) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL13870220 | 0.91 | PDE4B (0.58) | PDE4BPDE3BPDE7APDE3A | |
| Hydrochloric Acid SCHEMBL2773651 | 0.91 | PDE4B (0.62) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL2774432 | 0.90 | PDE4B (0.56) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL221173 | 0.89 | PDE4B (0.61) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL2775159 | 0.89 | PDE4B (0.55) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL13870254 | 0.88 | PDE4B (0.54) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL222815 | 0.87 | PDE4B (0.72) | PDE4B | |
| SCHEMBL2773212 | 0.86 | PDE4B (0.54) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL4330493 | 0.85 | PDE4B (0.73) | PDE4BPDE3BPDE7APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056823-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |