Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866353 | 0.90 | MCHR1 (0.44) | MCHR1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7046825 | 0.90 | MCHR1 (0.44) | MCHR1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8593949 | 0.85 | SMN1; SMN2 (0.50) | MCHR1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7313213 | 0.77 | SLC6A2 (0.50) | — | |
| SCHEMBL5866425 | 0.76 | NPC1 (0.49) | MCHR1HTTSMN1; SMN2HPGDPOLB | |
| SCHEMBL6161768 | 0.76 | NPC1 (0.49) | MCHR1HTTSMN1; SMN2HPGDPOLB | |
| Hydrochloric Acid SCHEMBL7745890 | 0.76 | SLC6A2 (0.49) | — | |
| SCHEMBL8118533 | 0.76 | MCHR1 (0.39) | MCHR1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8589980 | 0.75 | SMN1; SMN2 (0.53) | MCHR1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25261555 | 0.75 | SLC6A2 (0.46) | HTTALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591040-B1 | Quaternary basic amides as tachykinines antagonists | SANOFI SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| EP-0591040-A1 | Quaternary basic amides as tachykinines antagonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |