Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 5/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348868 | 0.82 | HSP90AA1 (0.52) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL8312961 | 0.78 | HSP90AA1 (0.46) | ALDH1A1MAPTHSP90AA1SMN1; SMN2LMNA | |
| SCHEMBL13012423 | 0.78 | HTR2C (0.57) | PNMTADRA2AADRA2BADRA2CCHRNB4 | |
| SCHEMBL13012422 | 0.78 | HTR2C (0.57) | PNMTADRA2AADRA2BADRA2CCHRNB4 | |
| SCHEMBL16691532 | 0.78 | HSP90AA1 (0.44) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL7509358 | 0.77 | HSP90AA1 (0.47) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL6478814 | 0.77 | HSP90AA1 (0.47) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL394579 | 0.77 | MEN1 (0.54) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL30073945 | 0.77 | HSP90AA1 (0.47) | ALDH1A1MAPTHSP90AA1PNMTADRA2A | |
| SCHEMBL23174854 | 0.77 | SLC6A2 (0.50) | ALDH1A1MAPTHSP90AA1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087124-A1 | COMPOUNDS HAVING SEROTONIN 5-HT17 RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC M4 RECEPTOR AGONIST ACTIVITY AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-14 | — | — | WO | disclosed |