Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83375 | 0.90 | JAK3 (0.43) | JAK3TP53LRRK2GRM4MAPT | |
| SCHEMBL395869 | 0.87 | HTT (0.37) | JAK3TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL394832 | 0.86 | PDE1B (0.41) | LRRK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL394833 | 0.86 | PDE1B (0.41) | LRRK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29368774 | 0.86 | PDE1B (0.41) | LRRK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL83557 | 0.86 | PDE1B (0.41) | LRRK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL83556 | 0.86 | PDE1B (0.41) | LRRK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL82988 | 0.85 | NPC1 (0.39) | JAK3TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL83554 | 0.85 | NPC1 (0.39) | JAK3TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL82635 | 0.85 | NPC1 (0.39) | JAK3TP53MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104883888-A | Compositions comprising biological control agents and pesticides | BAYER CROPSCIENCE AG | 2015-09-02 | — | — | CN | disclosed |
| US-8129526-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129526-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7973028-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7968537-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1622879-B1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITIONS CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-7928110-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1622879-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099160-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | C5, C1S, TYMS | JAK3 3395/4885TP53 2032/4885LRRK2 2664/4885 |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | JAK3 3176/4885TP53 2154/4885LRRK2 2024/4885 |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | JAK3 3111/4885TP53 2038/4885LRRK2 1931/4885 |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, CCNB3 | JAK3 1979/4885TP53 1224/4885LRRK2 2001/4885 |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | JAK3 3121/4885TP53 2131/4885LRRK2 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.