Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 4/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425902 | 0.87 | ACE (0.64) | ACEPPARAPPARGPPARD | |
| SCHEMBL13560712 | 0.87 | ACE (0.51) | ACEPPARAPPARGPPARD | |
| SCHEMBL9171784 | 0.83 | ACE (0.60) | ACEPPARAPPARGPPARD | |
| SCHEMBL9165661 | 0.83 | ACE (0.60) | ACEPPARAPPARGPPARD | |
| SCHEMBL11516592 | 0.83 | ACE (0.60) | ACEPPARAPPARGPPARD | |
| SCHEMBL8311397 | 0.82 | PPARA (0.45) | ACEPPARAPPARGPPARD | |
| SCHEMBL11516645 | 0.81 | ACE (0.60) | ACEPPARAPPARGPPARD | |
| SCHEMBL8658899 | 0.81 | ACE (0.63) | ACEPPARAPPARGPPARDFOLH1 | |
| SCHEMBL7282451 | 0.81 | ACE (0.67) | ACEPPARAPPARGPPARD | |
| SCHEMBL8658895 | 0.81 | ACE (0.63) | ACEPPARAPPARGPPARDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724601-A4 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORP (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0724601-A1 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995005398-A1 | S3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |