Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993122 | 0.84 | EGFR (0.60) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6989432 | 0.82 | STK17A (0.62) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6990324 | 0.81 | STK17A (0.59) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8315925 | 0.81 | EGFR (0.55) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6992551 | 0.81 | EGFR (0.59) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6990945 | 0.81 | EGFR (0.57) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8317956 | 0.80 | EGFR (0.56) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8317514 | 0.80 | EGFR (0.54) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8319127 | 0.80 | EGFR (0.54) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL8488667 | 0.80 | CSNK2A1 (0.62) | EGFRERBB2HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779888-B1 | PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-04-28 | — | — | EP | disclosed |