Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710708 | 0.91 | KMT2A (0.53) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL1181019 | 0.90 | KMT2A (0.63) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8716642 | 0.89 | KMT2A (0.51) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8711023 | 0.88 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8713770 | 0.88 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8711803 | 0.88 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL10792789 | 0.88 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8711063 | 0.88 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8712210 | 0.87 | KMT2A (0.59) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL16045767 | 0.82 | CA1 (0.43) | KMT2AMEN1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051077-C | Process for preparing benzo[c] phenanthridinium derivatives and compounds prepared by said process | NIPPON KAYAKU KK (JP) | 2000-04-05 | — | — | CN | disclosed |
| EP-0487930-B1 | Benzo[C]phenanthridinium derivatives | NIPPON KAYAKU KK (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5747502-A | ANTITUMOR AGENTS, ANTIGROWTH AGENTS AND ANTICARCINOGENIC AGENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1998-05-05 | — | — | US | disclosed |
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1061964-A | The preparation method of benzo [C] phenanthridines derivative and the new compound for preparing with described method | NIPPON KAYAKU KK (JP) | 1992-06-17 | — | — | CN | disclosed |
| EP-0487930-A1 | Process for preparing benzo[C]phenanthridinium derivatives, and novel compounds prepared by said process | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-06-03 | — | — | EP | disclosed |