Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 18/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072764 | 0.79 | DPP4 (0.70) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL1072765 | 0.79 | DPP4 (0.70) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4390625 | 0.78 | DPP4 (0.69) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4397350 | 0.77 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5519545 | 0.77 | DPP4 (0.68) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4865994 | 0.77 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL8334481 | 0.76 | DPP4 (0.71) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4387262 | 0.75 | DPP4 (0.66) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL3389459 | 0.75 | DPP4 (0.67) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL1072790 | 0.75 | DPP4 (0.67) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265128-B2 | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265128-B2 | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2007-09-04 | — | — | US | disclosed |
| WO-2004064778-A2 | 3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO. INC. (US) | 2004-08-05 | — | — | WO | disclosed |