Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316599 | 0.92 | AVPR2 (0.53) | AVPR1AAVPR2 | |
| SCHEMBL8311577 | 0.91 | AVPR1A (0.51) | AVPR1AAVPR2OXTR | |
| SCHEMBL8317666 | 0.90 | AVPR1A (0.46) | AVPR1AAVPR2 | |
| SCHEMBL7333364 | 0.90 | AVPR1A (0.61) | AVPR1AAVPR2OXTR | |
| SCHEMBL8318313 | 0.90 | AVPR2 (0.45) | AVPR1AAVPR2 | |
| SCHEMBL8316512 | 0.89 | MEN1 (0.48) | AVPR1AAVPR2OXTR | |
| SCHEMBL8315532 | 0.86 | AVPR1A (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL8318225 | 0.86 | AVPR1A (0.53) | AVPR1AAVPR2OXTR | |
| SCHEMBL8314230 | 0.84 | AVPR1A (0.48) | AVPR1AAVPR2OXTR | |
| SCHEMBL8315606 | 0.84 | AVPR1A (0.47) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |