⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456669 | 1.00 | — | — | |
| SCHEMBL14479181 | 1.00 | — | — | |
| SCHEMBL10019571 | 1.00 | — | — | |
| SCHEMBL31680384 | 1.00 | — | — | |
| SCHEMBL3634713 | 0.81 | SLC6A2 (0.35) | — | |
| SCHEMBL23373100 | 0.78 | — | — | |
| SCHEMBL12525053 | 0.78 | — | — | |
| SCHEMBL19050838 | 0.78 | — | — | |
| SCHEMBL22456311 | 0.78 | — | — | |
| SCHEMBL23705637 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021684-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. | 2023-01-26 | — | — | US | disclosed |
| WO-2019194858-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | ACHAOGEN, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| WO-2019046126-A1 | AMINOGLYCOSIDES AND USES THEREOF | ACHAOGEN, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| WO-2010030704-A2 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2004093821-A2 | TREATMENT OF ANTHRAX INFECTION USING INHIBITORS OF LETHAL FACTOR PROTEASE ACTIVITY | HAWAII BIOTECH, INC. (US) | 2004-11-04 | — | — | WO | disclosed |