Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798691 | 0.86 | GRM2 (0.65) | GRM2F10 | |
| SCHEMBL8948639 | 0.86 | GRM2 (0.65) | GRM2 | |
| SCHEMBL7237979 | 0.86 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8948817 | 0.86 | GRM2 (0.65) | GRM2 | |
| SCHEMBL9823590 | 0.81 | GRM2 (0.63) | GRM2F10 | |
| SCHEMBL2829551 | 0.80 | GRM2 (0.69) | GRM2 | |
| SCHEMBL6961314 | 0.79 | GRM2 (0.61) | GRM2 | |
| SCHEMBL9409330 | 0.79 | GRM2 (0.58) | GRM2 | |
| SCHEMBL2826188 | 0.79 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6956898 | 0.79 | GRM2 (0.61) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |