Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313242 | 0.94 | SLC6A4 (0.59) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8317788 | 0.93 | SLC6A4 (0.65) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8315402 | 0.90 | SLC6A4 (0.68) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8317286 | 0.89 | SLC6A4 (0.65) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8315879 | 0.88 | SLC6A4 (0.59) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL6985357 | 0.88 | SLC6A4 (0.58) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8316503 | 0.85 | SLC6A4 (0.61) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8317283 | 0.85 | SLC6A4 (0.60) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8312784 | 0.85 | SLC6A4 (0.60) | SLC6A4KDM4EGMNNALDH1A1LMNA | |
| SCHEMBL8317565 | 0.85 | SLC6A4 (0.62) | SLC6A4KDM4EGMNNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897921-A1 | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands | ELI LILLY AND COMPANY LIMITED (GB) | 1999-02-24 | — | — | EP | disclosed |